Archive | July, 2018

Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation

July 31, 2018

Comments Off on Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation

The mice were sacrificed on day 11 and the parameters described below were studied. Doxorubicin dose was selected on the basis of (a) when DOX used in combination with other chemotherapy drugs for the treatment of dif- ferent type of cancer, the most commonly used dosage of doxorubicin is 60–75mg/m2 IV once every 21 days. […]

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